[not in handout, see intranet]

Woodruff-Pak, D. S. (1993). Eyeblink Classical-Conditioning in H M - Delay and Trace Paradigms. Behavioral Neuroscience, 107(6), 911-925.

H.M., a well-known subject with bilateral removal of medial-temporal-lobe structures and profound amnesia, performed eyeblink classical conditioning for 21 90-trial sessions in the 400-ms delay and 900-ms trace paradigms. A 2nd amnesic subject with temporal lobe lesions and 2 normal control subjects (NCSs) were also conditioned. Acquisition occurred in both paradigms for all subjects.... Two years after initial conditioning, H.M. attained learning criterion in the trace paradigm in 1/10th as many trials. No recollection of the experimenters, apparatus, instructions, or procedure was manifested by H.M. Results suggest that humans can condition in these paradigms with the hippocampus radically excised.