Classical conditioning of Metabolic responses (animals)
(page 11 of handout)
UCS was presence of insulin in an injection.
CS was getting an injection + being placed in a holding cage smelling of mentholatum (for 20 mins, after which blood sample was taken from the tail)
The reference for this was left off the paper handout. It is
Russell, M., Dark, K. A., Cummins, R. W., Ellman, G., Calloway, E. and Peeke, H. V. S. (1984). Learned histamine release. Science, 225, 733—4.
Guinea pigs tested for plasma histamine release – 10 minutes after a trial animal was anaesthetised and blood withdrawn for testing
US was bovine serum albumen
CS+ and CS- were sulphur and fish smells — only one (CS+) paired with the US
Trials given one week apart
Extinction is produced if the cues given without the drug i.e. saline injections in room bring back the original effects of the same dose of morphine, but when saline is first given the rats are jump and hypersensitive, suggesting that an anti-sedation effect is still present (Siegel, 1975).
See Gleitman (1995, page 114; 1999, p. 126)
cf stimulus-substitution theory
What is associated may vary — different components of the UCR may be moved to the CR, and what is produced as the CR may also depend upon the precise characteristics of the signal and “affective responses”.